Novo Nordisk Shares Plunge After Heart Drug Ziltivekimab Fails Late-Stage Trial
On July 31, 2026, Novo Nordisk announced its experimental heart drug ziltivekimab failed to reduce major adverse cardiovascular events in a Phase 3 trial involving over 6,300 high-risk patients. The stock fell up to 10%, wiping out over $30 billion in market value. The failure removes a key non-obesity growth opportunity, as the company faces intense competition from Eli Lilly and a 70% share decline from its mid-2024 peak.