Inter Milan lost 2-1 away to Real Madrid in the opening match of the Champions League league phase, extending their losing streak against Real Madrid to five matches. Despite dominating possession with 64% and recording 21 shots, Real Madrid created more big chances and secured the win. The defeat also extended Inter's winless run to 14 consecutive Champions League away games against La Liga teams.
- Inter lost 2-1 away to Real Madrid in the Champions League opener, marking a fifth straight defeat against the Spanish side.
- Inter held 64% possession and took 21 shots, but Real Madrid created 8 big chances compared to Inter's 4.
- The result extended Inter's winless streak in Champions League away matches against La Liga teams to 14 games.
- Real Madrid fans booed Vinícius Júnior and Kylian Mbappé during the match, prompting manager José Mourinho to defend the players afterward.